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Serum biomarker concentrations over time after TBI. Serum levels of (A) MFGE8, (B) GFAP, and (C) the GFAP/MFGE8 ratio were measured in healthy controls and at admission, 24 h, 48 h, and 72 h after TBI. Data are presented as scatter-box plots (median with interquartile range) with log 10 -transformed concentrations.

Journal: Frontiers in Neurology

Article Title: Serial assessment of the novel biomarker MFGE8 in comparison with GFAP for predicting severity and outcome after traumatic brain injury

doi: 10.3389/fneur.2026.1750940

Figure Lengend Snippet: Serum biomarker concentrations over time after TBI. Serum levels of (A) MFGE8, (B) GFAP, and (C) the GFAP/MFGE8 ratio were measured in healthy controls and at admission, 24 h, 48 h, and 72 h after TBI. Data are presented as scatter-box plots (median with interquartile range) with log 10 -transformed concentrations.

Article Snippet: Serum levels of MFGE8 (E-EL-H2063) and GFAP (E-EL-H6093) were measured using a double-antibody sandwich ELISA (Elabscience Biotechnology Co., Ltd).

Techniques: Biomarker Discovery, Transformation Assay

Temporal distribution of serum MFGE8 and GFAP levels, and the GFAP/MFGE8 ratio across TBI severity groups based on GCS scores. Serum levels of MFGE8, GFAP, and the GFAP/MFGE8 ratio in patients with (A) mild, (B) moderate, and (C) severe TBI (stratified by GCS) at admission and at 24, 48, and 72 h post-injury. Each row represents a distinct TBI severity group. Data are presented as scatter-box plots (median with interquartile range) with log 10 -transformed concentrations.

Journal: Frontiers in Neurology

Article Title: Serial assessment of the novel biomarker MFGE8 in comparison with GFAP for predicting severity and outcome after traumatic brain injury

doi: 10.3389/fneur.2026.1750940

Figure Lengend Snippet: Temporal distribution of serum MFGE8 and GFAP levels, and the GFAP/MFGE8 ratio across TBI severity groups based on GCS scores. Serum levels of MFGE8, GFAP, and the GFAP/MFGE8 ratio in patients with (A) mild, (B) moderate, and (C) severe TBI (stratified by GCS) at admission and at 24, 48, and 72 h post-injury. Each row represents a distinct TBI severity group. Data are presented as scatter-box plots (median with interquartile range) with log 10 -transformed concentrations.

Article Snippet: Serum levels of MFGE8 (E-EL-H2063) and GFAP (E-EL-H6093) were measured using a double-antibody sandwich ELISA (Elabscience Biotechnology Co., Ltd).

Techniques: Transformation Assay

Temporal profiles of serum MFGE8 and GFAP levels stratified by clinical outcomes. Line charts depict the temporal trajectories of serum (A) MFGE8 and (B) GFAP concentrations stratified by clinical outcomes, categorized as favorable alive (GOSE 5–8), unfavorable alive (GOSE 2–4), and death (GOSE 1), measured at admission and at 24, 48, and 72 h after traumatic brain injury. Data points represent median values, and shaded areas indicate the interquartile range (IQR).

Journal: Frontiers in Neurology

Article Title: Serial assessment of the novel biomarker MFGE8 in comparison with GFAP for predicting severity and outcome after traumatic brain injury

doi: 10.3389/fneur.2026.1750940

Figure Lengend Snippet: Temporal profiles of serum MFGE8 and GFAP levels stratified by clinical outcomes. Line charts depict the temporal trajectories of serum (A) MFGE8 and (B) GFAP concentrations stratified by clinical outcomes, categorized as favorable alive (GOSE 5–8), unfavorable alive (GOSE 2–4), and death (GOSE 1), measured at admission and at 24, 48, and 72 h after traumatic brain injury. Data points represent median values, and shaded areas indicate the interquartile range (IQR).

Article Snippet: Serum levels of MFGE8 (E-EL-H2063) and GFAP (E-EL-H6093) were measured using a double-antibody sandwich ELISA (Elabscience Biotechnology Co., Ltd).

Techniques:

ROC curve analysis of MFGE8, GFAP, and the GFAP/MFGE8 ratio for predicting 30-day mortality risk.

Journal: Frontiers in Neurology

Article Title: Serial assessment of the novel biomarker MFGE8 in comparison with GFAP for predicting severity and outcome after traumatic brain injury

doi: 10.3389/fneur.2026.1750940

Figure Lengend Snippet: ROC curve analysis of MFGE8, GFAP, and the GFAP/MFGE8 ratio for predicting 30-day mortality risk.

Article Snippet: Serum levels of MFGE8 (E-EL-H2063) and GFAP (E-EL-H6093) were measured using a double-antibody sandwich ELISA (Elabscience Biotechnology Co., Ltd).

Techniques: